Leukotriene is one example of an eicosanoid. "Eicosanoids" is a collective term for prostaglandin and related compounds. They are referred to as the "local hormones" of the body. They have various roles in the regulation of the immune system.
Classification
Leukotrienes are classified into two types: cysteinyl and non-cysteinyl. Cysteinyl leukotrienes include C4, D4 and E4, while the non-cysteinyl leukotriene is B4.
Synthesis
The synthesis of leukotrienes follows a linear pathway initially catalyzed by the action of a specific enzyme, lipoxygenase. The arachidonic acid serves as the raw material and the leukocytes as the primary synthesizer.
